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human notch3 elisa kit  (Cusabio)


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    Structured Review

    Cusabio human notch3 elisa kit
    Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that <t>Notch3</t> is predominantly expressed in arterial tissues.
    Human Notch3 Elisa Kit, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+notch3+elisa+kit/Human+Neurogenic+locus+notch+homolog+protein+3(NOTCH3)+ELISA+kit/pmc11760494-165-13-17
    Average 92 stars, based on 2 article reviews
    human notch3 elisa kit - by Bioz Stars, 2026-09
    92/100 stars

    Images

    1) Product Images from "Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke"

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    Journal: QJM: An International Journal of Medicine

    doi: 10.1093/qjmed/hcae136

    Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that Notch3 is predominantly expressed in arterial tissues.
    Figure Legend Snippet: Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that Notch3 is predominantly expressed in arterial tissues.

    Techniques Used: Biomarker Assay, Isolation, Generated, Expressing

    Plasma NOTCH3 predicts cardiovascular recurrence in men with ischemic stroke. NOTCH3 protein levels were measured directly in plasma samples of ( A ) the discovery cohort comparing levels among ischemic stroke patients with and without events (Event+ and Event−, respectively), and in ( B ) a larger validation cohort comparing plasma NOTCH3 in ischemic stroke patients with and without events (Event+ and Event−, respectively) and age-matched healthy controls. ( C ) The Kaplan–Meier plot shows survival probability of men with ischemic stroke according to quartiles of plasma NOTCH3 (log-rank P values = 0.020) suggesting that individuals in the highest quartile (>1600 pg/ml) of plasma NOTCH3 are more likely to experience cardiovascular recurrence. Statistical analysis was performed using Student’s t -test with Bonferroni adjustments, where * P < 0.05, ** P < 0.01 and *** P < 0.001.
    Figure Legend Snippet: Plasma NOTCH3 predicts cardiovascular recurrence in men with ischemic stroke. NOTCH3 protein levels were measured directly in plasma samples of ( A ) the discovery cohort comparing levels among ischemic stroke patients with and without events (Event+ and Event−, respectively), and in ( B ) a larger validation cohort comparing plasma NOTCH3 in ischemic stroke patients with and without events (Event+ and Event−, respectively) and age-matched healthy controls. ( C ) The Kaplan–Meier plot shows survival probability of men with ischemic stroke according to quartiles of plasma NOTCH3 (log-rank P values = 0.020) suggesting that individuals in the highest quartile (>1600 pg/ml) of plasma NOTCH3 are more likely to experience cardiovascular recurrence. Statistical analysis was performed using Student’s t -test with Bonferroni adjustments, where * P < 0.05, ** P < 0.01 and *** P < 0.001.

    Techniques Used:

    Comparison in demographic, stroke characteristics, risk factors, laboratory investigations and cardiovascular events in men and women <xref ref-type= a " title="Comparison in demographic, stroke characteristics, risk factors, laboratory investigations and cardiovascular events in ... " property="contentUrl" width="100%" height="100%"/>
    Figure Legend Snippet: Comparison in demographic, stroke characteristics, risk factors, laboratory investigations and cardiovascular events in men and women a

    Techniques Used: Comparison, Cell Counting, Biomarker Assay

    The hazard ratio (HR) and 95% confidence intervals (CI) of cardiovascular recurrence were analyzed based on plasma NOTCH3 quartiles a
    Figure Legend Snippet: The hazard ratio (HR) and 95% confidence intervals (CI) of cardiovascular recurrence were analyzed based on plasma NOTCH3 quartiles a

    Techniques Used:

    NOTCH3 expression shows increased levels in mouse models of stroke and atherosclerosis. ( A ) Serial densitometric analysis and quantification of NOTCH3 protein in mouse serum following middle cerebral artery occlusion revealed a peak in NOTCH3 levels at 24 h, which continued to persist up to 72 h after cerebral reperfusion. Two technical replicates and pooled serum from six mice. ( B ) Representative immunofluorescence images of the innominate arteries of 22-week-old wild-type mice and Apoe-/- mice with advanced atherosclerotic plaque were examined. The images show NOTCH3-expressing endothelial cells in association with the plaque region. White arrowheads were used to indicate the location of these NOTCH3-expressing endothelial cells ( n = 3; L, lumen; P, plaque region). The scale bar represents 20 µm. ( C ) A quantification was performed to assess the number of NOTCH3-expressing endothelial cells in 14–20 analyzed arterial sections across three wild-type mice compared to three Apoe-/- mice. Data represent mean ± standard deviation; one-way ANOVA analysis; ** P < 0.01; *** P < 0.001; ns, non-significant.
    Figure Legend Snippet: NOTCH3 expression shows increased levels in mouse models of stroke and atherosclerosis. ( A ) Serial densitometric analysis and quantification of NOTCH3 protein in mouse serum following middle cerebral artery occlusion revealed a peak in NOTCH3 levels at 24 h, which continued to persist up to 72 h after cerebral reperfusion. Two technical replicates and pooled serum from six mice. ( B ) Representative immunofluorescence images of the innominate arteries of 22-week-old wild-type mice and Apoe-/- mice with advanced atherosclerotic plaque were examined. The images show NOTCH3-expressing endothelial cells in association with the plaque region. White arrowheads were used to indicate the location of these NOTCH3-expressing endothelial cells ( n = 3; L, lumen; P, plaque region). The scale bar represents 20 µm. ( C ) A quantification was performed to assess the number of NOTCH3-expressing endothelial cells in 14–20 analyzed arterial sections across three wild-type mice compared to three Apoe-/- mice. Data represent mean ± standard deviation; one-way ANOVA analysis; ** P < 0.01; *** P < 0.001; ns, non-significant.

    Techniques Used: Expressing, Immunofluorescence, Standard Deviation

    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke
    Article Snippet: .. We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients. ..

    Clinical Proteomics:

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke
    Article Snippet: .. We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients. ..



    Similar Products

    human notch3 elisa kit  (Cusabio)
    92
    Cusabio human notch3 elisa kit
    Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that <t>Notch3</t> is predominantly expressed in arterial tissues.
    Human Notch3 Elisa Kit, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+notch3+elisa+kit/Human+Neurogenic+locus+notch+homolog+protein+3(NOTCH3)+ELISA+kit/pmc11760494-165-13-17
    Average 92 stars, based on 1 article reviews
    human notch3 elisa kit - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that Notch3 is predominantly expressed in arterial tissues.

    Journal: QJM: An International Journal of Medicine

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    doi: 10.1093/qjmed/hcae136

    Figure Lengend Snippet: Biomarker discovery by quantitative proteomics. ( A ) Plasma microvesicle isolation was carried out based on the vascular event outcomes of ischemic stroke patients, following a specific workflow. ( B ) A heatmap was generated to display the differentially upregulated proteins in the Event+ and Event− groups, respectively, where P < 0.05. ( C ) The differentially expressed proteins underwent pathway analysis using the PANTHER Classification System. ( D ) The Genotype-Tissue Expression (GTEx) portal revealed that Notch3 is predominantly expressed in arterial tissues.

    Article Snippet: We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients.

    Techniques: Biomarker Assay, Isolation, Generated, Expressing

    Plasma NOTCH3 predicts cardiovascular recurrence in men with ischemic stroke. NOTCH3 protein levels were measured directly in plasma samples of ( A ) the discovery cohort comparing levels among ischemic stroke patients with and without events (Event+ and Event−, respectively), and in ( B ) a larger validation cohort comparing plasma NOTCH3 in ischemic stroke patients with and without events (Event+ and Event−, respectively) and age-matched healthy controls. ( C ) The Kaplan–Meier plot shows survival probability of men with ischemic stroke according to quartiles of plasma NOTCH3 (log-rank P values = 0.020) suggesting that individuals in the highest quartile (>1600 pg/ml) of plasma NOTCH3 are more likely to experience cardiovascular recurrence. Statistical analysis was performed using Student’s t -test with Bonferroni adjustments, where * P < 0.05, ** P < 0.01 and *** P < 0.001.

    Journal: QJM: An International Journal of Medicine

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    doi: 10.1093/qjmed/hcae136

    Figure Lengend Snippet: Plasma NOTCH3 predicts cardiovascular recurrence in men with ischemic stroke. NOTCH3 protein levels were measured directly in plasma samples of ( A ) the discovery cohort comparing levels among ischemic stroke patients with and without events (Event+ and Event−, respectively), and in ( B ) a larger validation cohort comparing plasma NOTCH3 in ischemic stroke patients with and without events (Event+ and Event−, respectively) and age-matched healthy controls. ( C ) The Kaplan–Meier plot shows survival probability of men with ischemic stroke according to quartiles of plasma NOTCH3 (log-rank P values = 0.020) suggesting that individuals in the highest quartile (>1600 pg/ml) of plasma NOTCH3 are more likely to experience cardiovascular recurrence. Statistical analysis was performed using Student’s t -test with Bonferroni adjustments, where * P < 0.05, ** P < 0.01 and *** P < 0.001.

    Article Snippet: We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients.

    Techniques:

    Comparison in demographic, stroke characteristics, risk factors, laboratory investigations and cardiovascular events in men and women <xref ref-type= a " width="100%" height="100%">

    Journal: QJM: An International Journal of Medicine

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    doi: 10.1093/qjmed/hcae136

    Figure Lengend Snippet: Comparison in demographic, stroke characteristics, risk factors, laboratory investigations and cardiovascular events in men and women a

    Article Snippet: We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients.

    Techniques: Comparison, Cell Counting, Biomarker Assay

    The hazard ratio (HR) and 95% confidence intervals (CI) of cardiovascular recurrence were analyzed based on plasma NOTCH3 quartiles a

    Journal: QJM: An International Journal of Medicine

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    doi: 10.1093/qjmed/hcae136

    Figure Lengend Snippet: The hazard ratio (HR) and 95% confidence intervals (CI) of cardiovascular recurrence were analyzed based on plasma NOTCH3 quartiles a

    Article Snippet: We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients.

    Techniques:

    NOTCH3 expression shows increased levels in mouse models of stroke and atherosclerosis. ( A ) Serial densitometric analysis and quantification of NOTCH3 protein in mouse serum following middle cerebral artery occlusion revealed a peak in NOTCH3 levels at 24 h, which continued to persist up to 72 h after cerebral reperfusion. Two technical replicates and pooled serum from six mice. ( B ) Representative immunofluorescence images of the innominate arteries of 22-week-old wild-type mice and Apoe-/- mice with advanced atherosclerotic plaque were examined. The images show NOTCH3-expressing endothelial cells in association with the plaque region. White arrowheads were used to indicate the location of these NOTCH3-expressing endothelial cells ( n = 3; L, lumen; P, plaque region). The scale bar represents 20 µm. ( C ) A quantification was performed to assess the number of NOTCH3-expressing endothelial cells in 14–20 analyzed arterial sections across three wild-type mice compared to three Apoe-/- mice. Data represent mean ± standard deviation; one-way ANOVA analysis; ** P < 0.01; *** P < 0.001; ns, non-significant.

    Journal: QJM: An International Journal of Medicine

    Article Title: Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

    doi: 10.1093/qjmed/hcae136

    Figure Lengend Snippet: NOTCH3 expression shows increased levels in mouse models of stroke and atherosclerosis. ( A ) Serial densitometric analysis and quantification of NOTCH3 protein in mouse serum following middle cerebral artery occlusion revealed a peak in NOTCH3 levels at 24 h, which continued to persist up to 72 h after cerebral reperfusion. Two technical replicates and pooled serum from six mice. ( B ) Representative immunofluorescence images of the innominate arteries of 22-week-old wild-type mice and Apoe-/- mice with advanced atherosclerotic plaque were examined. The images show NOTCH3-expressing endothelial cells in association with the plaque region. White arrowheads were used to indicate the location of these NOTCH3-expressing endothelial cells ( n = 3; L, lumen; P, plaque region). The scale bar represents 20 µm. ( C ) A quantification was performed to assess the number of NOTCH3-expressing endothelial cells in 14–20 analyzed arterial sections across three wild-type mice compared to three Apoe-/- mice. Data represent mean ± standard deviation; one-way ANOVA analysis; ** P < 0.01; *** P < 0.001; ns, non-significant.

    Article Snippet: We first sought to validate our previous findings using a commercial ELISA assay (Human NOTCH3 ELISA kit, Cusabio) on plasma samples from the same group of patients.

    Techniques: Expressing, Immunofluorescence, Standard Deviation